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Alzheimer

Einstein Health Library

What is Alzheimer's Disease?

Alzheimer's Disease is the most common form of dementia worldwide. It is identified by a series of changes in the brain that cause damage to brain cells. Although it is more common in the elderly, it can also occur in rare cases in younger patients.

Symptoms

The symptoms of Alzheimer's Disease can vary in intensity and severity, but generally include:

  • Memory loss: Forgetfulness is one of the first and most characteristic symptoms of the disease. The person may have difficulty remembering recent information, names, events, and daily details
  • Communication difficulties: The ability to communicate verbally decreases as the disease progresses. This can manifest as difficulty finding words, forming sentences, or understanding what others are saying
  • Difficulties in daily activities: Everyday tasks, such as dressing, preparing meals, bathing, and personal hygiene, become increasingly challenging
  • Reasoning difficulties: The ability to perform simple calculations or follow complex instructions may decrease

Causes

The exact causes of Alzheimer's Disease are not fully understood, but a combination of genetic, environmental, and lifestyle factors may play an important role in the development of the disease. Some aspects that have been associated with the disease are:

  • Age: It is the greatest risk factor for the condition. The chance of developing Alzheimer's Disease increases significantly with aging
  • Family history: Having first-degree relatives, such as parents or siblings with Alzheimer's Disease, is also a risk factor for the disease
  • Environment and lifestyle: Some lifestyle factors and environmental exposure can increase the risk of the disease. This includes smoking, lack of physical activity, obesity, and exposure to pollution

Diagnosis

The diagnosis of Alzheimer's Disease involves a detailed medical evaluation, which generally requires the collaboration of professionals such as neurologists.

The main steps in the diagnostic process are:

  • Clinical interview: The responsible professional seeks information about symptoms, medical history, and family history. This helps identify possible risk factors and understand the progression of the disease
  • Physical examination: To assess the patient's general health and rule out other medical conditions that may contribute to the symptoms
  • Imaging tests: Magnetic resonance imaging (MRI) and computed tomography (CT) are tests that can be performed to identify abnormalities in the brain
  • Laboratory evaluation: Blood tests may be performed to assess glucose levels, kidney function, liver function, and other factors that may affect brain function

Treatment

The treatment of Alzheimer's Disease is challenging, as there is no definitive cure. However, there are strategies and approaches that can help improve the patient's quality of life:

  • Speech therapy: Helps the person with the disease maintain communication skills, even as the disease progresses
  • Psychosocial support: Psychosocial support is essential, both for the patient and caregivers. This can include counseling, support groups, and education about the disease
  • Healthy lifestyle: A balanced diet, regular physical exercise, and challenging mental activities can help delay the progression of the disease

There are medications with over 25 years of use that slow the progression of the disease. In the past two years, treatment options have emerged that aim to stabilize the disease (already in use in the United States but not yet approved for use in Brazil).

Prevention

The prevention of Alzheimer's Disease still does not have a definitive method, as the exact causes of the disease are not fully understood. However, several prevention strategies help in this process:

  • Physical exercise: Regular activity helps keep the body healthy and prevent diseases. Aerobic exercises, such as walking, assist in this task
  • Healthy diet: Fruits, vegetables, fish, nuts, and olive oil are brain-healthy foods and help in prevention.
  • Control blood pressure: Hypertension can be a risk factor for Alzheimer's
  • Control diabetes: Type 2 is associated with a high risk, and keeping it controlled is essential in preventing the disease

References

Ministério da Saúde

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